Chronic Wasting Disease Found in White-tailed Deer Virginia

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Chronic Wasting Disease Found in White-tailed Deer Virginia

Postby flounder » Sat Jan 23, 2010 2:09 pm

Greetings Virginia Hunters,


I am very sorry to inform you of this. Your first case of CWD. please do not take this disease lightly. ...



Thursday, January 21, 2010 Chronic Wasting Disease Found in White-tailed Deer in Virginia

News Release For Immediate Release 1/20/2010 Contact Nelson Lafon, Deer Project Leader (Nelson.Lafon@dgif.virginia.gov), 540-248-9360 Cale Godfrey, Wildlife Division Assistant Director (Cale.Godfrey@dgif.virginia.gov), 804-367-6482

Chronic Wasting Disease Found in White-tailed Deer in Virginia The Virginia Department of Game and Inland Fisheries (VDGIF) received laboratory confirmation on January 19, 2010, that a white-tailed deer tested positive for chronic wasting disease (CWD). This is the first confirmed case of CWD in Virginia. The deer was killed by a hunter in Frederick County less than one mile from the West Virginia line. With this case, Virginia now joins 17 other states and Canadian provinces with CWD, five of which are east of the Mississippi River.

"This was not unexpected," stated VDGIF Executive Director Bob Duncan. "Our wildlife professionals have been preparing for this for some time. The surveillance efforts have been critical and we appreciate the hunters, check station operators, and other cooperators who have supported our efforts."

CWD is a disease of deer and has not been found to be transmitted to humans or other animals. To learn more about CWD in Virginia and about the agency's CWD Response Plan visit www.dgif.virginia.gov/cwd.

This is the first positive test sample out of nearly 5,000 deer tested in the Commonwealth since 2001. VDGIF has been sampling hunter-killed and road-killed deer from the Active Surveillance Area in western Frederick and Shenandoah counties since 2005, when CWD was first detected near Slanesville, West Virginia, within ten miles of the state line. Between 2005 and 2009, CWD has been detected in 62 deer in Hampshire County, West Virginia, out of nearly 10,000 total deer sampled during that time. Several have been found within five miles of the Virginia line.

Agency officials from West Virginia Division of Natural Resources (WVDNR) and VDGIF continue to share information and coordinate their responses. For more information on CWD in West Virginia please see the WVDNR website at http://www.wvdnr.org/. VDGIF is also working in consultation with the U.S. Department of Agriculture and the Virginia Department of Agriculture and Consumer Services.

How did VDGIF detect CWD in Virginia?

Since 2002, when CWD was first detected east of the Mississippi River (in Wisconsin), the Department developed a CWD Response Plan. Parts of the plan have been activated since 2005, after West Virginia discovered CWD. The Response Plan has been updated and revised several times, as recently as December 2009, as new information becomes available. The VDGIF CWD Response Plan is designed to define the magnitude and geographic extent of a CWD outbreak and control the transmission of the disease.

The 2-year-old female deer that tested positive was killed by a hunter on November 14, 2009, on private land west of Gore, Virginia, in Frederick County less than one mile from the West Virginia line. As part of VDGIF's CWD surveillance program, the hunter submitted the harvested deer for tissue sampling by VDGIF staff working at a local check station. VDGIF submitted samples to two different laboratories, first for initial testing, and then for independent confirmation.

Testing generally takes 6-8 weeks

VDGIF obtained 206 samples from hunter-killed and road-killed deer in the Active Surveillance Area near West Virginia during the 2009-10 hunting season. The agency is awaiting initial laboratory results for 37 of these samples taken at the end of the season. Hunters who submitted deer heads for tissue samples to test for CWD can check on results by visiting the Department's website at www.dgif.virginia.gov/cwdresults. VDGIF cannot guarantee that all hunter-submitted animals were tested.

What is CWD? Are people at risk?

CWD is a slow, progressive neurological (brain and nervous system) disease found in deer, elk, and moose in North America. The disease ultimately results in death. Species known to be susceptible include elk, red deer, moose, mule deer, white-tailed deer, and black-tailed deer. CWD belongs to a family of diseases known as transmissible spongiform encephalopathies. There is no evidence that CWD can be naturally transmitted to livestock or other (non deer) animals.

There is no current scientific evidence that CWD has ever infected humans. However, it is recommended that human exposure to the CWD agent be avoided, and the Department recommends that hunters take simple precautions such as not consuming any deer that appear abnormal or sick, and wearing gloves when field dressing and boning out the meat. In addition, it is recommended that hunters avoid consuming meat and tissues from known CWD-infected animals.

It must be remembered that the CWD test is designed for surveillance purposes and is not a food safety test. The CWD tests will detect the causative agent at a certain level in the tissue, and a result of "not detected" does not guarantee that the agent is not present at low levels.

How is VDGIF addressing CWD detection in Virginia?

The new detection in Frederick County, Virginia, will further activate the VDGIF CWD Response Plan which enhances surveillance and disease control measures. The CWD Response Plan is available on the Department website at www.dgif.virginia.gov/cwd.

VDGIF Executive Director Bob Duncan noted, "For many years, Department staff and our Board of Game and Inland Fisheries have been proactive in working to reduce Virginia's CWD risk."

Prevention and early detection remain important components of Virginia's CWD program. Given that CWD is likely transmitted deer-to-deer or through environmental contamination by infected deer, activities that unnaturally concentrate deer or move deer or deer carcasses likely increase the risk of spreading CWD. Therefore, since 2002, VDGIF has:

1) Actively conducted CWD surveillance activities throughout Virginia , and targeted surveillance of suspected risk factors; 2) Changed regulations and permit conditions to ban the importation of live deer and elk into and within Virginia; 3) Strengthened captive deer requirements related to animal marking, record keeping, facility inspections, and mortality reporting; 4) Prohibited the importation of whole deer carcasses and selected parts into Virginia from states known to have CWD; 5) Prohibited the feeding of deer in Virginia from September 1 through the first weekend in January each year; 6) Prohibited the relocation of rehabilitated deer out of Frederick or Shenandoah counties; 7) Provided accurate and timely information about CWD to deer hunters and the general public through news releases, pamphlets, magazine articles and other media outlets.

Persons who have questions or need additional information about CWD should visit the Department's website at www.dgif.virginia.gov/cwd.

http://www.dgif.virginia.gov/news/release.asp?id=246

Friday, January 15, 2010

Sixteen Additional Deer Test Positive for Chronic Wasting Disease In Hampshire County, West Virginia
flounder
 
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A Weighted Surveillance Approach for Detecting Chronic Wasti

Postby flounder » Thu Jan 28, 2010 1:13 pm

Journal of Wildlife Diseases, 46(1), 2010, pp. 118-135
© Wildlife Disease Association 2010


A Weighted Surveillance Approach for Detecting Chronic Wasting Disease Foci

Daniel P. Walsh1,2 and Michael W. Miller1
1 Wildlife Health Program, Colorado Division of Wildlife, Wildlife Research Center, 317 West Prospect Road, Fort Collins, Colorado 80526-2097, USA
2 Corresponding author (email: dan.walsh@state.co.us )

ABSTRACT: A key component of wildlife disease surveillance is determining the spread and geographic extent of pathogens by monitoring for infected individuals in regions where cases have not been previously detected. A practical challenge of such surveillance is developing reliable, yet cost-effective, approaches that remain sustainable when monitoring needs are prolonged or continuous, or when resources to support these efforts are limited. In order to improve the efficiency of chronic wasting disease (CWD) surveillance in Colorado, United States, we developed a weighted surveillance system exploiting observed differences in CWD prevalence across demographic strata within infected mule deer (Odocoileus hemionus) populations. We used field data to estimate sampling weights for individuals from eight demographic strata distinguished by differences in apparent health, sex, and age. In this system, individuals from a sample source with high prevalence and low inclusion probability (e.g., clinical CWD "suspects") received 10.3 times more weight than those from a source with low prevalence and high inclusion probability (e.g., apparently healthy, hunter-harvested individuals). We simulated use of this alternative surveillance system for a deer management unit in Colorado and evaluated the potential effects of using biased weights on the probability of failing to detect CWD and on relative surveillance costs. We found that this system should be transparent, cost-effective, and reasonably robust to the inadvertent use of biased weights. By implementing this, or a similar, weighted surveillance system, wildlife agencies should be able to maintain or improve current surveillance standards while, perhaps, collecting and examining fewer samples, thereby increasing the efficiency and cost-effectiveness of ongoing CWD surveillance programs.


Key words: Chronic wasting disease, disease detection, mule deer, Odocoileus hemionus, prion, sampling, weighted surveillance.





http://www.jwildlifedis.org/cgi/content ... type=HWCIT
flounder
 
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Aerosol and Nasal Transmission of CWD in Cervidized Mice

Postby flounder » Mon Feb 22, 2010 10:32 am

Published online ahead of print on 17 February 2010 as doi:10.1099/vir.0.017335-0 J Gen Virol (2010), DOI 10.1099/vir.0.017335-0 © 2010 Society for General Microbiology

Aerosol and Nasal Transmission of Chronic Wasting Disease in Cervidized Mice

Nathaniel D Denkers1, Davis M Seelig1, Glenn C. Telling2 and Edward A Hoover, Jr1,3

1 Colorado State University; 2 University of Kentucky Medical Center

3 E-mail: edward.hoover@colostate.edu

Little is known regarding the potential risk posed by aerosolized prions. Chronic wasting disease (CWD) is transmitted horizontally, almost surely by mucosal exposure, and CWD prions are present in saliva and urine of infected animals. However, whether CWD may be transmissible by the aerosol or nasal route is not known. To address this question, FVB mice transgenetically expressing the normal cervid PrPC protein [Tg(cerPrP) mice] were exposed to CWD prions by either nose-only aerosol exposure or by drop-wise instillation into the nostrils. Mice were monitored for signs of disease for up to 755 days post inoculation (dpi) and by examination of tissues for lesions and PrPCWD after necropsy. In particular, nasal mucosa, vomeronasal organ, lungs, lymphoid tissue, and the brain were assessed for PrPCWD by western blotting and immunohistochemistry. Six of 7 aerosol-exposed Tg(cerPrP) mice developed clinical signs of neurologic dysfunction mandating euthanasia between 411 and 749 dpi. In all these mice, CWD infection was confirmed by detection of spongiform lesions and PrPCWD in the brain. Two of 9 intra-nasally inoculated Tg(cerPrP) mice also developed TSE associated with PrPCWD between 417 and 755 dpi. No evidence of PrPCWD was detected in CWD-inoculated Tg(cerPrP) mice examined at pre-terminal time points. These results demonstrate that CWD can be transmitted by aerosol (as well as nasal) exposure and suggest that exposure via the respiratory system merits consideration for prion disease transmission and biosafety.

Received 30 October 2009; accepted 15 February 2010.


http://vir.sgmjournals.org/cgi/content/ ... 017335-0v1
flounder
 
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Re: Chronic Wasting Disease Found in White-tailed Deer Virgi

Postby baysider » Mon Nov 01, 2010 6:32 pm

We had the disease hit the Eastern Shore a couple years ago. The herd here is way over populated and hunting land is becoming hard to obtain. Most of the local farms have been leased to people that arent from here and only trophy hunt. Ive noticed that the average kill weight has decreased by 20 lbs in the last 15 years. The disease CWD has hit 2 times here in the last 15 years. Its a bad sight to walk into the woods and find 10-15 deer dead together. Nothing to take lightly. Herd management instead of antler management is key to keeping disease down in over populated areas. For the past 3 years we have been working with the surrounding hunter to our property and taking as many of the older does and bucks out. I have seen a slight imporvment but it is hard when most of the 1000's of acres surrounding us are hunted by 2-3 that take only one or two deer a year. Take notice trophy hunters....conservation of the herd isnt always letting them walk.
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